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Characterization of Antibacterial and Hemolytic Activity of Synthetic Pandinin 2 Variants and Their Inhibition against Mycobacterium tuberculosis

The contention and treatment of Mycobacterium tuberculosis and other bacteria that cause infectious diseases require the use of new type of antibiotics. Pandinin 2 (Pin2) is a scorpion venom antimicrobial peptide highly hemolytic that has a central proline residue. This residue forms a structural “k...

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Detalles Bibliográficos
Autores principales: Rodríguez, Alexis, Villegas, Elba, Montoya-Rosales, Alejandra, Rivas-Santiago, Bruno, Corzo, Gerardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096598/
https://www.ncbi.nlm.nih.gov/pubmed/25019413
http://dx.doi.org/10.1371/journal.pone.0101742