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Integrative analysis of differential miRNA and functional study of miR-21 by seed-targeting inhibition in multiple myeloma cells in response to berberine

BACKGROUND: Berberine is a natural alkaloid derived from a traditional Chinese herbal medicine. It is known to modulate microRNA (miRNA) levels, although the mechanism for this action is unknown. Here, we previously demonstrate that the expression of 87 miRNAs is differentially affected by berberine...

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Detalles Bibliográficos
Autores principales: Luo, Xiaochuang, Gu, Jingyi, Zhu, Rongxuan, Feng, Maoxiao, Zhu, Xuejiao, Li, Yumin, Fei, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096730/
https://www.ncbi.nlm.nih.gov/pubmed/25000828
http://dx.doi.org/10.1186/1752-0509-8-82