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Integrative analysis of differential miRNA and functional study of miR-21 by seed-targeting inhibition in multiple myeloma cells in response to berberine
BACKGROUND: Berberine is a natural alkaloid derived from a traditional Chinese herbal medicine. It is known to modulate microRNA (miRNA) levels, although the mechanism for this action is unknown. Here, we previously demonstrate that the expression of 87 miRNAs is differentially affected by berberine...
Autores principales: | Luo, Xiaochuang, Gu, Jingyi, Zhu, Rongxuan, Feng, Maoxiao, Zhu, Xuejiao, Li, Yumin, Fei, Jia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096730/ https://www.ncbi.nlm.nih.gov/pubmed/25000828 http://dx.doi.org/10.1186/1752-0509-8-82 |
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