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The Anti-Apoptotic and Cardioprotective Effects of Salvianolic Acid A on Rat Cardiomyocytes following Ischemia/Reperfusion by DUSP-Mediated Regulation of the ERK1/2/JNK Pathway

The purpose of this study was to observe the effects of salvianolic acid A (SAA) pretreatment on the myocardium during ischemia/reperfusion (I/R) and to illuminate the interrelationships among dual specificity protein phosphatase (DUSP) 2/4/16, ERK1/2 and JNK pathways during myocardial I/R, with the...

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Detalles Bibliográficos
Autores principales: Xu, Tongda, Wu, Xin, Chen, Qiuping, Zhu, Shasha, Liu, Yang, Pan, Defeng, Chen, Xiaohu, Li, Dongye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096914/
https://www.ncbi.nlm.nih.gov/pubmed/25019380
http://dx.doi.org/10.1371/journal.pone.0102292