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Changes in Liver Cell DNA Methylation Status in Diabetic Mice Affect Its FT-IR Characteristics

BACKGROUND: Lower levels of cytosine methylation have been found in the liver cell DNA from non-obese diabetic (NOD) mice under hyperglycemic conditions. Because the Fourier transform-infrared (FT-IR) profiles of dry DNA samples are differently affected by DNA base composition, single-stranded form...

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Detalles Bibliográficos
Autores principales: Vidal, Benedicto de Campos, Ghiraldini, Flávia Gerelli, Mello, Maria Luiza S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096918/
https://www.ncbi.nlm.nih.gov/pubmed/25019512
http://dx.doi.org/10.1371/journal.pone.0102295