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Changes in Liver Cell DNA Methylation Status in Diabetic Mice Affect Its FT-IR Characteristics
BACKGROUND: Lower levels of cytosine methylation have been found in the liver cell DNA from non-obese diabetic (NOD) mice under hyperglycemic conditions. Because the Fourier transform-infrared (FT-IR) profiles of dry DNA samples are differently affected by DNA base composition, single-stranded form...
Autores principales: | Vidal, Benedicto de Campos, Ghiraldini, Flávia Gerelli, Mello, Maria Luiza S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096918/ https://www.ncbi.nlm.nih.gov/pubmed/25019512 http://dx.doi.org/10.1371/journal.pone.0102295 |
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