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Yeast Augmented Network Analysis (YANA): a new systems approach to identify therapeutic targets for human genetic diseases

Genetic interaction networks that underlie most human diseases are highly complex and poorly defined. Better-defined networks will allow identification of a greater number of therapeutic targets. Here we introduce our Yeast Augmented Network Analysis (YANA) approach and test it with the X-linked spi...

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Detalles Bibliográficos
Autores principales: Wiley, David J., Juan, Ilona, Le, Hao, Cai, Xiaodong, Baumbach, Lisa, Beattie, Christine, D'Urso, Gennaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097366/
https://www.ncbi.nlm.nih.gov/pubmed/25075304
http://dx.doi.org/10.12688/f1000research.4188.1