Cell-Permeable Parkin Proteins Suppress Parkinson Disease-Associated Phenotypes in Cultured Cells and Animals

Parkinson’s disease (PD) is a neurodegenerative disorder of complex etiology characterized by the selective loss of dopaminergic neurons, particularly in the substantia nigra. Parkin, a tightly regulated E3 ubiquitin ligase, promotes the survival of dopaminergic neurons in both PD and Parkinsonian s...

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Detalles Bibliográficos
Autores principales: Duong, Tam, Kim, Jaetaek, Ruley, H. Earl, Jo, Daewoong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097392/
https://www.ncbi.nlm.nih.gov/pubmed/25019626
http://dx.doi.org/10.1371/journal.pone.0102517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097392/
https://www.ncbi.nlm.nih.gov/pubmed/25019626
http://dx.doi.org/10.1371/journal.pone.0102517

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