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Exogenous Oct-4 Inhibits Lens Transdifferentiation in the Newt Notophthalmus viridescens
From the cocktail of four factors that were able to induce pluripotent stem cells from differentiated cells, Oct-4, c-Myc, Sox-2 and Klf4, only Oct-4 was not expressed during regeneration in newts. To explore the possible action of this stemness factor we developed an assay where we introduced exoge...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097451/ https://www.ncbi.nlm.nih.gov/pubmed/25019378 http://dx.doi.org/10.1371/journal.pone.0102510 |