Development and validation of a new high-throughput method to investigate the clonality of HTLV-1-infected cells based on provirus integration sites

Transformation and clonal proliferation of T-cells infected with human T-cell leukemia virus type-I (HTLV-1) cause adult T-cell leukemia. We took advantage of next-generation sequencing technology to develop and internally validate a new methodology for isolating integration sites and estimating the...

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Detalles Bibliográficos
Autores principales: Firouzi, Sanaz, López, Yosvany, Suzuki, Yutaka, Nakai, Kenta, Sugano, Sumio, Yamochi, Tadanori, Watanabe, Toshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097847/
https://www.ncbi.nlm.nih.gov/pubmed/25028597
http://dx.doi.org/10.1186/gm568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097847/
https://www.ncbi.nlm.nih.gov/pubmed/25028597
http://dx.doi.org/10.1186/gm568

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