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Formulation and evaluation of sustained release matrix tablet of rabeprazole using wet granulation technique

INTRODUCTION: Rabeprazole, a member of substituted benzimidazoles, inhibits the final step in gastric acid secretions. This drug claims to cause fastest acid separation (due to higher pKa), and more rapidly converts to the active species to aid gastric mucin synthesis. The most significant pharmacol...

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Detalles Bibliográficos
Autores principales: Khan, Ruqaiyah, Ashraf, Md Shamim, Afzal, Muhammad, Kazmi, Imran, Jahangir, Mohammed Asadullah, Singh, Rajbala, Chandra, Ramesh, Anwar, Firoz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097931/
https://www.ncbi.nlm.nih.gov/pubmed/25035637
http://dx.doi.org/10.4103/0975-7406.130961