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Application of synthetic photostable retinoids induces novel limb and facial phenotypes during chick embryogenesis in vivo

We have recently developed a range of synthetic retinoid analogues which include the compounds EC23 and EC19. They are stable on exposure to light and are predicted to be resistant to the normal metabolic processes involved in the inactivation of retinoids in vivo. Based on the position of the termi...

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Detalles Bibliográficos
Autores principales: Lopez-Real, R E, Budge, J J R, Marder, T B, Whiting, A, Hunt, P N, Przyborski, S A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098675/
https://www.ncbi.nlm.nih.gov/pubmed/24303996
http://dx.doi.org/10.1111/joa.12147