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A novel approach to identify driver genes involved in androgen-independent prostate cancer

BACKGROUND: Insertional mutagenesis screens have been used with great success to identify oncogenes and tumor suppressor genes. Typically, these screens use gammaretroviruses (γRV) or transposons as insertional mutagens. However, insertional mutations from replication-competent γRVs or transposons t...

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Detalles Bibliográficos
Autores principales: Schinke, Ellyn N, Bii, Victor, Nalla, Arun, Rae, Dustin T, Tedrick, Laura, Meadows, Gary G, Trobridge, Grant D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098713/
https://www.ncbi.nlm.nih.gov/pubmed/24885513
http://dx.doi.org/10.1186/1476-4598-13-120