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Multiple signaling pathways regulate contractile activity‐mediated PGC‐1α gene expression and activity in skeletal muscle cells

PGC‐1α is an important transcriptional coactivator that plays a key role in mediating mitochondrial biogenesis. Within seconds of the onset of contractile activity, a number of rapid cellular events occur that form part of the initial signaling processes involved in PGC‐1α gene regulation, such as e...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Uguccioni, Giulia, Ljubicic, Vladimir, Irrcher, Isabella, Iqbal, Sobia, Singh, Kaustabh, Ding, Shuzhe, Hood, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098736/
https://www.ncbi.nlm.nih.gov/pubmed/24843073
http://dx.doi.org/10.14814/phy2.12008