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Impact of glucose dosing regimens on modeling of glucose tolerance and β‐cell function by intravenous glucose tolerance test in diet‐induced obese mice

Insulin sensitivity declines in overweight and obese individuals and, under normal conditions, insulin secretion adaptively increases which in healthy non‐diabetic subjects maintains normal glycemia. This adaptation is best described by the disposition index derived from modeling of insulin and gluc...

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Detalles Bibliográficos
Autores principales: Omar, Bilal A., Pacini, Giovanni, Ahrén, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098739/
https://www.ncbi.nlm.nih.gov/pubmed/24843074
http://dx.doi.org/10.14814/phy2.12011