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Quantum coupled mutation finder: predicting functionally or structurally important sites in proteins using quantum Jensen-Shannon divergence and CUDA programming

BACKGROUND: The identification of functionally or structurally important non-conserved residue sites in protein MSAs is an important challenge for understanding the structural basis and molecular mechanism of protein functions. Despite the rich literature on compensatory mutations as well as sequenc...

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Detalles Bibliográficos
Autores principales: Gültas, Mehmet, Düzgün, Güncel, Herzog, Sebastian, Jäger, Sven Joachim, Meckbach, Cornelia, Wingender, Edgar, Waack, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098773/
https://www.ncbi.nlm.nih.gov/pubmed/24694117
http://dx.doi.org/10.1186/1471-2105-15-96