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proNGF/NGF mixtures induce gene expression changes in PC12 cells that neither singly produces

BACKGROUND: Growing evidence shows that, in vivo, the precursor of Nerve Growth Factor (NGF), proNGF, displays biological activities different from those of its mature NGF counterpart, mediated by distinct, and somewhat complementary, receptor binding properties. NGF and proNGF induce distinct trans...

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Detalles Bibliográficos
Autores principales: Arisi, Ivan, D’Onofrio, Mara, Brandi, Rossella, Malerba, Francesca, Paoletti, Francesca, Storti, Andrea Ennio, Florenzano, Fulvio, Fasulo, Luisa, Cattaneo, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098786/
https://www.ncbi.nlm.nih.gov/pubmed/24713110
http://dx.doi.org/10.1186/1471-2202-15-48