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Mannosylated Chitosan Nanoparticles for Delivery of Antisense Oligonucleotides for Macrophage Targeting

The therapeutic potential of antisense oligonucleotides (ASODN) is primarily dependent upon its safe and efficient delivery to specific cells overcoming degradation and maximizing cellular uptake in vivo. The present study focuses on designing mannosylated low molecular weight (LMW) chitosan nanocon...

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Detalles Bibliográficos
Autores principales: Shilakari Asthana, Gyati, Asthana, Abhay, Kohli, Dharm Veer, Vyas, Suresh Prasad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098891/
https://www.ncbi.nlm.nih.gov/pubmed/25057492
http://dx.doi.org/10.1155/2014/526391