Genetic Testing in Hereditary Breast and Ovarian Cancer Using Massive Parallel Sequencing

High throughput methods such as next generation sequencing are increasingly used in molecular diagnosis. The aim of this study was to develop a workflow for the detection of BRCA1 and BRCA2 mutations using massive parallel sequencing in a 454 GS Junior bench top sequencer. Our approach was first val...

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Detalles Bibliográficos
Autores principales: Ruiz, Anna, Llort, Gemma, Yagüe, Carmen, Baena, Neus, Viñas, Marina, Torra, Montse, Brunet, Anna, Seguí, Miquel A., Saigí, Eugeni, Guitart, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098986/
https://www.ncbi.nlm.nih.gov/pubmed/25136594
http://dx.doi.org/10.1155/2014/542541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098986/
https://www.ncbi.nlm.nih.gov/pubmed/25136594
http://dx.doi.org/10.1155/2014/542541

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