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Increased Oxidative Damage Associated with Unfavorable Cytogenetic Subgroups in Chronic Lymphocytic Leukemia

Oxidative stress contributes to genomic instability in chronic lymphocytic leukemia (CLL), but its relationship with the acquisition of specific chromosomal abnormalities is unknown. We recruited 55 untreated CLL patients and assessed 8-oxo-2′-deoxyguanosine (8-oxo-dG), glutathione, and malondialdeh...

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Detalles Bibliográficos
Autores principales: Collado, Rosa, Ivars, David, Oliver, Isabel, Tormos, Carmen, Egea, Mercedes, Miguel, Amparo, Sáez, Guillermo T., Carbonell, Félix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099055/
https://www.ncbi.nlm.nih.gov/pubmed/25054143
http://dx.doi.org/10.1155/2014/686392