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ERCC1 Cys8092Ala and XRCC1 Arg399Gln Polymorphisms Predict Progression-Free Survival after Curative Radiotherapy for Nasopharyngeal Carcinoma

BACKGROUND: Single nucleotide polymorphisms (SNPs) in DNA repair genes can alter gene expression and activity and affect response to cancer treatment and, correspondingly, survival. The present study was designed to evaluate the utility of the XRCC1 Arg399Gln and ERCC1 Cys8092Ala SNPs, measured in p...

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Detalles Bibliográficos
Autores principales: Jin, Hekun, Xie, Xiaoxue, Wang, Hui, Hu, Jun, Liu, Feng, Liu, Zhigang, Zhou, Jumei, Zhang, Yingying, Xi, Xuping, Hu, Bingqiang, Liao, Yuping, Tang, Jingtian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099069/
https://www.ncbi.nlm.nih.gov/pubmed/25025378
http://dx.doi.org/10.1371/journal.pone.0101256