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Palmitoylation of Gephyrin Controls Receptor Clustering and Plasticity of GABAergic Synapses
Postsynaptic scaffolding proteins regulate coordinated neurotransmission by anchoring and clustering receptors and adhesion molecules. Gephyrin is the major instructive molecule at inhibitory synapses, where it clusters glycine as well as major subsets of GABA type A receptors (GABA(A)Rs). Here, we...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099074/ https://www.ncbi.nlm.nih.gov/pubmed/25025157 http://dx.doi.org/10.1371/journal.pbio.1001908 |