Palmitoylation of Gephyrin Controls Receptor Clustering and Plasticity of GABAergic Synapses

Postsynaptic scaffolding proteins regulate coordinated neurotransmission by anchoring and clustering receptors and adhesion molecules. Gephyrin is the major instructive molecule at inhibitory synapses, where it clusters glycine as well as major subsets of GABA type A receptors (GABA(A)Rs). Here, we...

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Detalles Bibliográficos
Autores principales: Dejanovic, Borislav, Semtner, Marcus, Ebert, Silvia, Lamkemeyer, Tobias, Neuser, Franziska, Lüscher, Bernhard, Meier, Jochen C., Schwarz, Guenter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099074/
https://www.ncbi.nlm.nih.gov/pubmed/25025157
http://dx.doi.org/10.1371/journal.pbio.1001908

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