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Nanoformulated cell-penetrating survivin mutant and its dual actions

In this study, we investigated the differential actions of a dominant-negative survivin mutant (SurR9-C84A) against cancerous SK-N-SH neuroblastoma cell lines and differentiated SK-N-SH neurons. In both the cases, the mutant protein displayed dual actions, where its effects were cytotoxic toward can...

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Detalles Bibliográficos
Autores principales: Sriramoju, Bhasker, Kanwar, Rupinder K, Kanwar, Jagat R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099198/
https://www.ncbi.nlm.nih.gov/pubmed/25045261
http://dx.doi.org/10.2147/IJN.S60169