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Visualization of Phosphatidic Acid Fluctuations in the Plasma Membrane of Living Cells

We developed genetically-encoded fluorescent sensors based on Förster Resonance Energy Transfer to monitor phosphatidic acid (PA) fluctuations in the plasma membrane using Spo20 as PA-binding motif. Basal PA levels and phospholipase D activity varied in different cell types. In addition, stimuli tha...

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Detalles Bibliográficos
Autores principales: Ferraz-Nogueira, José P., Díez-Guerra, F. Javier, Llopis, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099201/
https://www.ncbi.nlm.nih.gov/pubmed/25025521
http://dx.doi.org/10.1371/journal.pone.0102526