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Host Cytokine Responses Induced after Overnight Stimulation with Novel M. tuberculosis Infection Phase-Dependent Antigens Show Promise as Diagnostic Candidates for TB Disease

BACKGROUND: We previously identified Mycobacterium tuberculosis (M.tb) antigen-induced host markers that showed promise as TB diagnostic candidates in 7-day whole blood culture supernatants. The aim of the present study was to evaluate the utility of these markers further, and cross-compare results...

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Detalles Bibliográficos
Autores principales: Essone, Paulin N., Chegou, Novel N., Loxton, Andre G., Stanley, Kim, Kriel, Magdalena, van der Spuy, Gian, Franken, Kees L., Ottenhoff, Tom H., Walzl, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099213/
https://www.ncbi.nlm.nih.gov/pubmed/25025278
http://dx.doi.org/10.1371/journal.pone.0102584