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Efficacy of Imiquimod-Based Transcutaneous Immunization Using a Nano-Dispersed Emulsion Gel Formulation

BACKGROUND: Transcutaneous immunization (TCI) approaches utilize skin associated lymphatic tissues to elicit specific immune responses. In this context, the imidazoquinoline derivative imiquimod formulated in Aldara applied onto intact skin together with a cytotoxic T lymphocyte (CTL) epitope induce...

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Detalles Bibliográficos
Autores principales: Stein, Pamela, Gogoll, Karsten, Tenzer, Stefan, Schild, Hansjörg, Stevanovic, Stefan, Langguth, Peter, Radsak, Markus P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099367/
https://www.ncbi.nlm.nih.gov/pubmed/25025233
http://dx.doi.org/10.1371/journal.pone.0102664