Novel Missense Variants of ZFPM2/FOG2 Identified in Conotruncal Heart Defect Patients Do Not Impair Interaction with GATA4

Conotruncal heart defect (CTD) is a complex form of congenital heart disease and usually has a poor prognosis. ZFPM2/FOG2 encodes a transcription cofactor that interacts with GATA4 to regulate cardiac development. This regulation has been established in knockout mouse models that display a range of...

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Detalles Bibliográficos
Autores principales: Zhang, Wenwen, Shen, Li, Deng, Zhantao, Ding, Yibing, Mo, Xuming, Xu, Zhengfeng, Gao, Qian, Yi, Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099368/
https://www.ncbi.nlm.nih.gov/pubmed/25025186
http://dx.doi.org/10.1371/journal.pone.0102379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099368/
https://www.ncbi.nlm.nih.gov/pubmed/25025186
http://dx.doi.org/10.1371/journal.pone.0102379

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