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Lactate and the Lactate-to-Pyruvate Molar Ratio Cannot Be Used as Independent Biomarkers for Monitoring Brain Energetic Metabolism: A Microdialysis Study in Patients with Traumatic Brain Injuries

BACKGROUND: For decades, lactate has been considered an excellent biomarker for oxygen limitation and therefore of organ ischemia. The aim of the present study was to evaluate the frequency of increased brain lactate levels and the LP ratio (LPR) in a cohort of patients with severe or moderate traum...

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Detalles Bibliográficos
Autores principales: Sahuquillo, Juan, Merino, Maria-Angels, Sánchez-Guerrero, Angela, Arikan, Fuat, Vidal-Jorge, Marian, Martínez-Valverde, Tamara, Rey, Anna, Riveiro, Marilyn, Poca, Maria-Antonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099374/
https://www.ncbi.nlm.nih.gov/pubmed/25025772
http://dx.doi.org/10.1371/journal.pone.0102540