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Lactate and the Lactate-to-Pyruvate Molar Ratio Cannot Be Used as Independent Biomarkers for Monitoring Brain Energetic Metabolism: A Microdialysis Study in Patients with Traumatic Brain Injuries
BACKGROUND: For decades, lactate has been considered an excellent biomarker for oxygen limitation and therefore of organ ischemia. The aim of the present study was to evaluate the frequency of increased brain lactate levels and the LP ratio (LPR) in a cohort of patients with severe or moderate traum...
Autores principales: | Sahuquillo, Juan, Merino, Maria-Angels, Sánchez-Guerrero, Angela, Arikan, Fuat, Vidal-Jorge, Marian, Martínez-Valverde, Tamara, Rey, Anna, Riveiro, Marilyn, Poca, Maria-Antonia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099374/ https://www.ncbi.nlm.nih.gov/pubmed/25025772 http://dx.doi.org/10.1371/journal.pone.0102540 |
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