Aβ and tau toxicities in Alzheimer’s are linked via oxidative stress-induced p38 activation: Protective role of vitamin E

Oxidative stress is a hallmark of Alzheimer’s disease (AD). We propose that rather than causing damage because of the action of free radicals, oxidative stress deranges signaling pathways leading to tau hyperphosphorylation, a hallmark of the disease. Indeed, incubation of neurons in culture with 5 ...

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Detalles Bibliográficos
Autores principales: Giraldo, E., Lloret, A., Fuchsberger, T., Viña, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099506/
https://www.ncbi.nlm.nih.gov/pubmed/25061569
http://dx.doi.org/10.1016/j.redox.2014.03.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099506/
https://www.ncbi.nlm.nih.gov/pubmed/25061569
http://dx.doi.org/10.1016/j.redox.2014.03.002

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