Inactivation of the cardiomyocyte glucagon-like peptide-1 receptor (GLP-1R) unmasks cardiomyocyte-independent GLP-1R-mediated cardioprotection()()

GLP-1R agonists improve outcomes in ischemic heart disease. Here we studied GLP-1R-dependent adaptive and cardioprotective responses to ventricular injury. Glp1r(−/−) hearts exhibited chamber-specific differences in gene expression, but normal mortality and left ventricular (LV) remodeling after myo...

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Detalles Bibliográficos
Autores principales: Ussher, John R., Baggio, Laurie L., Campbell, Jonathan E., Mulvihill, Erin E., Kim, Minsuk, Kabir, M. Golam, Cao, Xiemin, Baranek, Benjamin M., Stoffers, Doris A., Seeley, Randy J., Drucker, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099509/
https://www.ncbi.nlm.nih.gov/pubmed/25061556
http://dx.doi.org/10.1016/j.molmet.2014.04.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099509/
https://www.ncbi.nlm.nih.gov/pubmed/25061556
http://dx.doi.org/10.1016/j.molmet.2014.04.009

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