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Methyl-donor supplementation in obese mice prevents the progression of NAFLD, activates AMPK and decreases acyl-carnitine levels()

Non-alcoholic fatty liver disease (NAFLD) results from increased hepatic lipid accumulation and steatosis, and is closely linked to liver one-carbon (C1) metabolism. We assessed in C57BL6/N mice whether NAFLD induced by a high-fat (HF) diet over 8 weeks can be reversed by additional 4 weeks of a die...

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Detalles Bibliográficos
Autores principales: Dahlhoff, Christoph, Worsch, Stefanie, Sailer, Manuela, Hummel, Björn A., Fiamoncini, Jarlei, Uebel, Kirsten, Obeid, Rima, Scherling, Christian, Geisel, Jürgen, Bader, Bernhard L., Daniel, Hannelore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099513/
https://www.ncbi.nlm.nih.gov/pubmed/25061561
http://dx.doi.org/10.1016/j.molmet.2014.04.010