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Chromatin-regulating proteins as targets for cancer therapy

Chromatin-regulating proteins represent a large class of novel targets for cancer therapy. In the context of radiotherapy, acetylation and deacetylation of histones by histone acetyltransferases (HATs) and histone deacetylases (HDACs) play important roles in the repair of DNA double-strand breaks ge...

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Detalles Bibliográficos
Autores principales: Oike, Takahiro, Ogiwara, Hideaki, Amornwichet, Napapat, Nakano, Takashi, Kohno, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099987/
https://www.ncbi.nlm.nih.gov/pubmed/24522270
http://dx.doi.org/10.1093/jrr/rrt227