Cargando…

Chromatin-regulating proteins as targets for cancer therapy

Chromatin-regulating proteins represent a large class of novel targets for cancer therapy. In the context of radiotherapy, acetylation and deacetylation of histones by histone acetyltransferases (HATs) and histone deacetylases (HDACs) play important roles in the repair of DNA double-strand breaks ge...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oike, Takahiro, Ogiwara, Hideaki, Amornwichet, Napapat, Nakano, Takashi, Kohno, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099987/ https://www.ncbi.nlm.nih.gov/pubmed/24522270 http://dx.doi.org/10.1093/jrr/rrt227

Ejemplares similares

Carbon-Ion Beam Irradiation Kills X-Ray-Resistant p53-Null Cancer Cells by Inducing Mitotic Catastrophe
por: Amornwichet, Napapat, et al.
Publicado: (2014)

The EGFR mutation status affects the relative biological effectiveness of carbon-ion beams in non-small cell lung carcinoma cells
por: Amornwichet, Napapat, et al.
Publicado: (2015)

Radiosensitivity Differences between EGFR Mutant and Wild-Type Lung Cancer Cells are Larger at Lower Doses
por: Anakura, Mai, et al.
Publicado: (2019)

Synthetic lethal therapy based on targeting the vulnerability of SWI/SNF chromatin remodeling complex‐deficient cancers
por: Sasaki, Mariko, et al.
Publicado: (2020)

Rectal irrigation as rescue therapy for refractory and severe hemorrhagic radiation proctitis: A case report
por: Pattarajierapan, Sukit, et al.
Publicado: (2021)

Essential Factors for Incompatible DNA End Joining at Chromosomal DNA Double Strand Breaks In Vivo
por: Ogiwara, Hideaki, et al.
Publicado: (2011)

CBP and p300 Histone Acetyltransferases Contribute to Homologous Recombination by Transcriptionally Activating the BRCA1 and RAD51 Genes
por: Ogiwara, Hideaki, et al.
Publicado: (2012)

Advanced radiotherapy technique in hepatocellular carcinoma with portal vein thrombosis: Feasibility and clinical outcomes
por: Khorprasert, Chonlakiet, et al.
Publicado: (2021)

Mitotic catastrophe is a putative mechanism underlying the weak correlation between sensitivity to carbon ions and cisplatin
por: Kobayashi, Daijiro, et al.
Publicado: (2017)

Polymyositis and fatal interstitial pneumonia following pelvic irradiation that led to unexpectedly severe adverse effects: a case report
por: Oike, Takahiro, et al.
Publicado: (2015)

One-step Protocol for Evaluation of the Mode of Radiation-induced Clonogenic Cell Death by Fluorescence Microscopy
por: Kobayashi, Daijiro, et al.
Publicado: (2017)

Translational Research to Improve the Efficacy of Carbon Ion Radiotherapy: Experience of Gunma University
por: Oike, Takahiro, et al.
Publicado: (2016)

Inter-assay precision of clonogenic assays for radiosensitivity in cancer cell line A549
por: Nuryadi, Endang, et al.
Publicado: (2018)

Machine learning-based normal tissue complication probability model for predicting albumin-bilirubin (ALBI) grade increase in hepatocellular carcinoma patients
por: Prayongrat, Anussara, et al.
Publicado: (2022)

Correction: Machine learning-based normal tissue complication probability model for predicting albumin-bilirubin (ALBI) grade increase in hepatocellular carcinoma patients
por: Prayongrat, Anussara, et al.
Publicado: (2023)

Targeting DNA Repair and Chromatin Crosstalk in Cancer Therapy
por: Johnson, Danielle P., et al.
Publicado: (2021)

Robustness of Clonogenic Assays as a Biomarker for Cancer Cell Radiosensitivity
por: Matsui, Toshiaki, et al.
Publicado: (2019)

Flattening filter free stereotactic body radiation therapy for lung tumors: outcomes and predictive factors
por: Jaruthien, Thitiporn, et al.
Publicado: (2021)

Role of Tricellular Tight Junction Protein Lipolysis-Stimulated Lipoprotein Receptor (LSR) in Cancer Cells
por: Kohno, Takayuki, et al.
Publicado: (2019)

Targeting Chromatin Remodeling for Cancer Therapy
por: Kaur, Jasmine, et al.
Publicado: (2019)

Clustered DNA double-strand break formation and the repair pathway following heavy-ion irradiation
por: Hagiwara, Yoshihiko, et al.
Publicado: (2019)

Targeting Chromatin-Remodeling Factors in Cancer Cells: Promising Molecules in Cancer Therapy
por: Zhang, Fang-Lin, et al.
Publicado: (2022)

Inhibition of the HDAC/Suv39/G9a pathway restores the expression of DNA damage-dependent major histocompatibility complex class I-related chain A and B in cancer cells
por: Nakajima, Nakako Izumi, et al.
Publicado: (2017)

Leptomeningeal metastasis of uterine cervical cancer 17 years after primary tumor treatment
por: Oike, Takahiro, et al.
Publicado: (2015)

IBS-GEC ESTRO-ABS recommendations for CT based contouring in image guided adaptive brachytherapy for cervical cancer
por: Mahantshetty, Umesh, et al.
Publicado: (2021)

Factors and Mechanisms That Influence Chromatin-Mediated Enhancer–Promoter Interactions and Transcriptional Regulation
por: Ito, Shinsuke, et al.
Publicado: (2022)

Use of a Si/CdTe Compton Camera for In vivo Real-Time Monitoring of Annihilation Gamma Rays Generated by Carbon Ion Beam Irradiation
por: Shiba, Shintaro, et al.
Publicado: (2020)

Nuclear Pore Proteins in Regulation of Chromatin State
por: Kuhn, Terra M., et al.
Publicado: (2019)

New Aspects of Magnesium Function: A Key Regulator in Nucleosome Self-Assembly, Chromatin Folding and Phase Separation
por: Ohyama, Takashi
Publicado: (2019)

Chromatin targeting drugs in cancer and immunity
por: Prinjha, Rab, et al.
Publicado: (2013)

High linear energy transfer carbon-ion irradiation increases the release of the immune mediator high mobility group box 1 from human cancer cells
por: Onishi, Masahiro, et al.
Publicado: (2018)

Comparison of hematological toxicities between innovator and generic cisplatin formulations in cervical cancer patients treated with concurrent chemoradiotherapy
por: Oike, Takahiro, et al.
Publicado: (2013)

Radiotherapy plus Concomitant Adjuvant Temozolomide for Glioblastoma: Japanese Mono-Institutional Results
por: Oike, Takahiro, et al.
Publicado: (2013)

Pre-Exposure to Ionizing Radiation Stimulates DNA Double Strand Break End Resection, Promoting the Use of Homologous Recombination Repair
por: Nakajima, Nakako Izumi, et al.
Publicado: (2015)

Identification of potential target genes for the tomato fruit-ripening regulator RIN by chromatin immunoprecipitation
por: Fujisawa, Masaki, et al.
Publicado: (2011)

Atypical Macropinocytosis Contributes to Malignant Progression: A Review of Recent Evidence in Endometrioid Endometrial Cancer Cells
por: Kohno, Takayuki, et al.
Publicado: (2022)

The chromatin-associated RNAs in gene regulation and cancer
por: Tang, Jun, et al.
Publicado: (2023)

HAUSP Is a Key Epigenetic Regulator of the Chromatin Effector Proteins
por: Abdullah, Omeima, et al.
Publicado: (2021)

Chromatin targeting of nuclear pore proteins induces chromatin decondensation
por: Kuhn, Terra M., et al.
Publicado: (2019)

Predictive factors of acute skin reactions to carbon ion radiotherapy for the treatment of malignant bone and soft tissue tumors
por: Takakusagi, Yosuke, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_bb3040em00s5796i9adrgtir32