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Cranial irradiation induces bone marrow-derived microglia in adult mouse brain tissue

Postnatal hematopoietic progenitor cells do not contribute to microglial homeostasis in adult mice under normal conditions. However, previous studies using whole-body irradiation and bone marrow (BM) transplantation models have shown that adult BM cells migrate into the brain tissue and differentiat...

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Detalles Bibliográficos
Autores principales: Okonogi, Noriyuki, Nakamura, Kazuhiro, Suzuki, Yoshiyuki, Suto, Nana, Suzue, Kazutomo, Kaminuma, Takuya, Nakano, Takashi, Hirai, Hirokazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100007/
https://www.ncbi.nlm.nih.gov/pubmed/24706998
http://dx.doi.org/10.1093/jrr/rru015