Cargando…

Hypersensitivity of mouse NEIL1-knockdown cells to hydrogen peroxide during S phase

Oxidative base damage occurs spontaneously due to reactive oxygen species generated as byproducts of respiration and other pathological processes in mammalian cells. Many oxidized bases are mutagenic and/or toxic, and most are repaired through the base excision repair pathway. Human endonuclease VII...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamamoto, Ryohei, Ohshiro, Yukari, Shimotani, Tatsuhiko, Yamamoto, Mizuki, Matsuyama, Satoshi, Ide, Hiroshi, Kubo, Kihei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100011/
https://www.ncbi.nlm.nih.gov/pubmed/24706997
http://dx.doi.org/10.1093/jrr/rru021