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Hypersensitivity of mouse NEIL1-knockdown cells to hydrogen peroxide during S phase
Oxidative base damage occurs spontaneously due to reactive oxygen species generated as byproducts of respiration and other pathological processes in mammalian cells. Many oxidized bases are mutagenic and/or toxic, and most are repaired through the base excision repair pathway. Human endonuclease VII...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100011/ https://www.ncbi.nlm.nih.gov/pubmed/24706997 http://dx.doi.org/10.1093/jrr/rru021 |