Systemic Injection of Low-Dose Lipopolysaccharide Fails to Break down the Blood–Brain Barrier or Activate the TLR4-MyD88 Pathway in Neonatal Rat Brain

We aimed to investigate whether peripheral low-dose lipopolysaccharide (LPS) induces the breakdown of the blood–brain barrier (BBB) and/or the activation of toll-like receptor 4 (TLR4) in the neonatal rat brain. Neonatal rats received intraperitoneal injections of low-dose LPS (0.3 mg/kg∙bw), and th...

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Detalles Bibliográficos
Autores principales: Wang, Peng, You, Si-Wei, Yang, Yin-Jie, Wei, Xiao-Yan, Wang, Ya-Zhou, Wang, Xin, Hao, Ding-Jun, Kuang, Fang, Shang, Li-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100142/
https://www.ncbi.nlm.nih.gov/pubmed/24905408
http://dx.doi.org/10.3390/ijms150610101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100142/
https://www.ncbi.nlm.nih.gov/pubmed/24905408
http://dx.doi.org/10.3390/ijms150610101

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