SUMOylation of FOXM1B Alters Its Transcriptional Activity on Regulation of MiR-200 Family and JNK1 in MCF7 Human Breast Cancer Cells

Transcription factor Forkhead Box Protein M1 (FOXM1) is a well-known master regulator in controlling cell-cycle pathways essential for DNA replication and mitosis, as well as cell proliferation. Among the three major isoforms of FOXM1, FOXM1B is highly associated with tumor growth and metastasis. Th...

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Detalles Bibliográficos
Autores principales: Wang, Chiung-Min, Liu, Runhua, Wang, Lizhong, Nascimento, Leticia, Brennan, Victoria C., Yang, Wei-Hsiung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100150/
https://www.ncbi.nlm.nih.gov/pubmed/24918286
http://dx.doi.org/10.3390/ijms150610233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100150/
https://www.ncbi.nlm.nih.gov/pubmed/24918286
http://dx.doi.org/10.3390/ijms150610233

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