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SUMOylation of FOXM1B Alters Its Transcriptional Activity on Regulation of MiR-200 Family and JNK1 in MCF7 Human Breast Cancer Cells
Transcription factor Forkhead Box Protein M1 (FOXM1) is a well-known master regulator in controlling cell-cycle pathways essential for DNA replication and mitosis, as well as cell proliferation. Among the three major isoforms of FOXM1, FOXM1B is highly associated with tumor growth and metastasis. Th...
Autores principales: | Wang, Chiung-Min, Liu, Runhua, Wang, Lizhong, Nascimento, Leticia, Brennan, Victoria C., Yang, Wei-Hsiung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100150/ https://www.ncbi.nlm.nih.gov/pubmed/24918286 http://dx.doi.org/10.3390/ijms150610233 |
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