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Triterpenoid Saponins from Stauntonia chinensis Ameliorate Insulin Resistance via the AMP-Activated Protein Kinase and IR/IRS-1/PI3K/Akt Pathways in Insulin-Resistant HepG2 Cells

Inflammation and oxidative stress play crucial roles in the etiology of type 2 diabetes mellitus. In this study, we examined the anti-diabetic effects of triterpenoid saponins extracted from Stauntonia chinensis on stimulating glucose uptake by insulin-resistant human HepG2 cells. The results showed...

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Detalles Bibliográficos
Autores principales: Hu, Xin, Wang, Sha, Xu, Jing, Wang, De-Bing, Chen, Yu, Yang, Guang-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100161/
https://www.ncbi.nlm.nih.gov/pubmed/24918297
http://dx.doi.org/10.3390/ijms150610446