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A-769662 Protects Osteoblasts from Hydrogen Dioxide-Induced Apoptosis through Activating of AMP-Activated Protein Kinase (AMPK)

Here we report that 5'-monophosphate (AMP)-activated protein kinase (AMPK) agonist A-769662 inhibited hydrogen peroxide (H(2)O(2))-induced viability loss and apoptosis of human and mouse osteoblast cells. H(2)O(2)-induced moderate AMPK activation in osteoblast cells, which was enhanced by A-769...

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Detalles Bibliográficos
Autores principales: Zhu, Yalong, Zhou, Jianhua, Ao, Rongguang, Yu, Baoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100207/
https://www.ncbi.nlm.nih.gov/pubmed/24960362
http://dx.doi.org/10.3390/ijms150611190