Rag GTPases are cardioprotective by regulating lysosomal function

The Rag family proteins are Ras-like small GTPases that play a critical role in amino acid-stimulated mTORC1 activation by recruiting mTORC1 to lysosome. Despite progress in the mechanistic understanding of Rag GTPases in mTORC1 activation, little is known about the physiological function of Rag GTP...

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Detalles Bibliográficos
Autores principales: Kim, Young Chul, Park, Hyun Woo, Sciarretta, Sebastiano, Mo, Jung-Soon, Jewell, Jenna L., Russell, Ryan C., Wu, Xiaohui, Sadoshima, Junichi, Guan, Kun-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100214/
https://www.ncbi.nlm.nih.gov/pubmed/24980141
http://dx.doi.org/10.1038/ncomms5241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100214/
https://www.ncbi.nlm.nih.gov/pubmed/24980141
http://dx.doi.org/10.1038/ncomms5241

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