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MMSET: Role and Therapeutic Opportunities in Multiple Myeloma

Recurrent chromosomal translocations are central to the pathogenesis, diagnosis, and prognosis of hematologic malignancies. The translocation t(4; 14)(p16; q32) is one of the most common translocations in multiple myeloma (MM) and is associated with very poor prognosis. The t(4; 14) translocation le...

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Detalles Bibliográficos
Autores principales: Xie, Zhigang, Chng, Wee Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100374/
https://www.ncbi.nlm.nih.gov/pubmed/25093175
http://dx.doi.org/10.1155/2014/636514