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Targeting the Neddylation Pathway to Suppress the Growth of Prostate Cancer Cells: Therapeutic Implication for the Men's Cancer

The neddylation pathway has been recognized as an attractive anticancer target in several malignancies, and its selective inhibitor, MLN4924, has recently advanced to clinical development. However, the anticancer effect of this compound against prostate cancer has not been well investigated. In this...

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Detalles Bibliográficos
Autores principales: Wang, Xiaofang, Li, Lihui, Liang, Yupei, Li, Chunjie, Zhao, Hu, Ye, Dingwei, Sun, Menghong, Jeong, Lak Shin, Feng, Yan, Fu, Shen, Jia, Lijun, Guo, Xiaomao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100379/
https://www.ncbi.nlm.nih.gov/pubmed/25093192
http://dx.doi.org/10.1155/2014/974309