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Necroptosis Mediates TNF-Induced Toxicity of Hippocampal Neurons

Tumor necrosis factor-α (TNF-α) is a critical proinflammatory cytokine regulating neuroinflammation. Elevated levels of TNF-α have been associated with various neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. However, the signaling events that lead to TNF-α-i...

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Detalles Bibliográficos
Autores principales: Liu, Shan, Wang, Xing, Li, Yun, Xu, Lei, Yu, Xiaoliang, Ge, Lin, Li, Jun, Zhu, Yongjin, He, Sudan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100394/
https://www.ncbi.nlm.nih.gov/pubmed/25093162
http://dx.doi.org/10.1155/2014/290182