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Metabolic Effects of Hypoxia in Colorectal Cancer by (13)C NMR Isotopomer Analysis

(13)C NMR isotopomer analysis was used to characterize intermediary metabolism in three colorectal cancer cell lines (WiDr, LS1034, and C2BBe1) and determine the “metabolic remodeling” that occurs under hypoxia. Under normoxia, the three colorectal cancer cell lines present high rates of lactate pro...

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Detalles Bibliográficos
Autores principales: Abrantes, Ana M., Tavares, Ludgero C., Pires, Salomé, Casalta-Lopes, João, Mendes, Cândida, Simões, Marta, Grazina, Manuela M., Carvalho, Rui A., Botelho, Maria Filomena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100400/
https://www.ncbi.nlm.nih.gov/pubmed/25093181
http://dx.doi.org/10.1155/2014/759791