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Effect of ingested human antibodies induced by RTS, S/AS01 malaria vaccination in children on Plasmodium falciparum oocyst formation and sporogony in mosquitoes

BACKGROUND: The circumsporozoite protein (CS protein) on the malaria parasites in mosquitoes plays an important role in sporogony in mosquitoes. The RTS,S/AS01 malaria vaccine candidate, which has shown significant efficacy against clinical malaria in a large Phase 3 trial, targets the Plasmodium fa...

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Detalles Bibliográficos
Autores principales: Miura, Kazutoyo, Jongert, Erik, Deng, Bingbing, Zhou, Luwen, Lusingu, John P, Drakeley, Chris J, Fay, Michael P, Long, Carole A, Vekemans, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100490/
https://www.ncbi.nlm.nih.gov/pubmed/25007730
http://dx.doi.org/10.1186/1475-2875-13-263