FBXO7 Y52C Polymorphism as a Potential Protective Factor in Parkinson's Disease

Mutations in the F-box only protein 7 gene (FBXO7), the substrate-specifying subunit of SCF E3 ubiquitin ligase complex, cause Parkinson's disease (PD)-15 (PARK15). To identify new variants, we sequenced FBXO7 cDNA in 80 Taiwanese early onset PD patients (age at onset ≤50) and only two known va...

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Detalles Bibliográficos
Autores principales: Chen, Chiung-Mei, Chen, I-Cheng, Huang, Yi-Cheng, Juan, Hsueh-Fen, Chen, Ying-Lin, Chen, Yi-Chun, Lin, Chih-Hsin, Lee, Li-Ching, Lee, Chi-Mei, Lee-Chen, Guey-Jen, Lai, Yun-Ju, Wu, Yih-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100735/
https://www.ncbi.nlm.nih.gov/pubmed/25029497
http://dx.doi.org/10.1371/journal.pone.0101392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100735/
https://www.ncbi.nlm.nih.gov/pubmed/25029497
http://dx.doi.org/10.1371/journal.pone.0101392

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